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Filtered Search Results
Cayman Chemical D-Pinitol, Purity: ≥95%, CAS: 10284-63-6, 5 g
A cyclitol with diverse biological activities; decreases NF-κB gene expression and induces DNA fragmentation and apoptosis in MCF-7 breast cancer cells; induces endothelium- and nitric oxide-dependent vasodilation in isolated mouse mesenteric arteries; reduces systolic blood pressure in mice at 10 mg/kg; enhances creatine clearance, reduces tubulointerstitial fibrosis, and increases levels of the cytosolic antioxidant enzymes SOD1 and NQO1 in a mouse model of cyclosporin A-induced nephropathy at 50 mg/kg; decreases plasma glucose levels in a mouse model of streptozotocin-induced diabetes
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Cayman Chemical Dexchlorpheniramine (maleate), Purity: ≥98%, CAS: 2438-32-6, 500 mg
A histamine H1 receptor antagonist (pA2 = 9.36 in guinea pig ileal tissue); inhibits specific allergen-challenged peripheral blood mononuclear cell proliferation by 92% in vitro (4.8 µM); reduces noradrenaline uptake in rat vas deferens ex vivo (10 µM); increases pain threshold in mice exposed to thermal and chemical stimulation (30 mg/kg, i.p.)
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Cayman Chemical 9(Z),11(Z)-Conjugated Linoleic Acid methyl ester, Purity: ≥96%, CAS: 822-10-6, 25 mg
A conjugated linoleic acid methyl ester; has been used as a standard for the quantification of conjugated linoleic acid methyl esters by GC-MS
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Cayman Chemical Ticarcillin (sodium salt), Purity: ≥95% (mixture of diastereomers), CAS: 4697-14-7, 1 g
A semi-synthetic β-lactam antibiotic; active against P. aeruginosa, E. coli, P. mirabilis, P. rettgeri, and K. aerogenes (MICs = 4-125 μg/ml); reduces P. aeruginosa colony count in rabbit eye at 2.5 mg/eye
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Cayman Chemical N2-Isobutyryl Guanosine, Purity: ≥95%, CAS: 64350-24-9, 10 g
A derivative of guanosine; a precursor in the synthesis of hydrophobic dinucleotide cap analogs used to purify capped mRNA; a precursor in the synthesis of photocaged 3’-S-RNAs used in the study of ribozyme-catalyzed reactions
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Cayman Chemical 1,2,3-Tri-13(E)-Docosenoyl Glycerol, Purity: ≥98%, CAS: 37635-44-2, 100 mg
A triacylglycerol; dietary administration at 15% of a calcium-deficient diet transiently increases heart triglyceride levels, which return to baseline after 28 days
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Cayman Chemical Oxybuprocaine (hydrochloride), Purity: ≥95%, CAS: 5987-82-6, 25 g
An anesthetic; reduces motor function, decreases righting behaviors in the placement test, and increases latency to paw withdrawal in the hot plate test when intrathecally administered in rats (ED50s = 0.43, 0.5, and 0.31 µmol/kg, respectively); reduces corneal sensitivity in the corneal touch test in dogs when topically applied at 0.4% w/v
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Cayman Chemical 1,2,3-Trilinoelaidoyl Glycerol, Purity: ≥98%, CAS: 5188-25-0, 100 mg
A triacylglycerol; dietary administration lowers serum levels of TXB2, PGF2, and PGE in rats from 0.6-6.3% w/w
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Cayman Chemical Dehydrocholic Acid, Purity: ≥95%, CAS: 81-23-2, 5 g
A synthetic bile acid and a derivative of cholic acid; increases bile flow by 2.7-fold and decreases biliary levels of phospholipids, cholesterol, and bilirubin in conscious dogs at 50 mg/kg; increases bile flow by 253% at 1 µmol/min/0.1 kg and decreases the secretion rate of phospholipids and cholesterol by 64 and 94%, respectively, in rats when infused intravenously at 2 µmol/min/0.1 kg
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Cayman Chemical 1,2,3-Tritridecanoyl Glycerol, Purity: ≥98%, CAS: 26536-12-9, 500 mg
A synthetic triacylglycerol; has been used as a standard for the relative quantification of triacylglycerols in C. elegans; has been used as an internal standard for the quantification of triacylglycerols in the serum and liver of adult rat offspring receiving dietary conjugated linoleic acids during and after gestation
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Cayman Chemical Cyclic di-AMP ELISA Standard, 15 ng
Cyclic di-AMP ELISA Standard has been tested and formulated to work exclusively with Cayman’s Cyclic di-AMP ELISA Kit
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Cayman Chemical D-Penicillamine, Purity: ≥98%, CAS: 52-67-5, 10 g
A chelating agent; increases urinary and fecal copper excretion and decreases liver copper concentration in a rat model of copper overload when administered at 0.67 mmol/kg per day; dissolves copper-rich granules in hepatic lysosomes of LEC rats (100 mg/kg per day); has anticonvulsant and proconvulsant effects in mice when administered at 0.5 and 250 mg/kg, respectively, which are blocked by the NOS inhibitors L-NAME and 7-nitroindazole
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Cayman Chemical 2,2’-Biquinoline-4,4’-dicarboxylic Acid (sodium salt), Purity: ≥98%, CAS: 979-88-4, 1 g
A colorimetric reagent for the detection of copper; with Cu+, forms a stable 2:1 complex that has an absorbance maximum at 562 nm; commonly used as a reagent in the colorimetric BCA protein quantitation assay
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Cayman Chemical 4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline, Purity: ≥95%, CAS: 183322-18-1, 250 mg
A building block and synthetic intermediate; has been used as a precursor in the synthesis of inhibitors, dual RTK and HDAC inhibitors, and anticancer compounds; a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib, with antiproliferative activity
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Cayman Chemical 5-Bromouridine, Purity: ≥98%, CAS: 957-75-5, 500 mg
A brominated uridine analog; can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine; decreases the viability of HL-60 and MOLT-4 cells (LC50s = 10 and 20 μM, respectively); induces apoptosis and halts the cell cycle at the S phase in HL-60 cells; photoreactive; UV irradiation has been used to cross-link RNA containing 5-bromouridine to proteins in the study of RNA-protein interactions; can be incorporated into RNA using 5-bromouridine 5’-triphosphate
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